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ORIGINAL ARTICLE
Year : 2018  |  Volume : 4  |  Issue : 3  |  Page : 127-132

Delivering personalized dietary advice for health management and disease prevention


Department of Precision Medicine, RowAnalytics Ltd, Oxford, England, UK

Correspondence Address:
Steve Gardner
RowAnalytics Ltd, C9 Glyme Court, Langford Lane, Kidlington, Oxford, OX5 1LQ
UK
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/digm.digm_19_18

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Background and Objectives: Diet plays a huge role in health, both by increasing metabolic disease risks and acutely through adverse interactions with diseases and medications. Multimorbid and polypharmaceutical patients are at a particularly high risk of such interactions due to the number of drugs they take. This leads to avoidable hospitalizations and poor compliance. This study built and demonstrated a tool that provides personalized dietary advice that accounts for a patient's combination of disease and drugs in real-time on their mobile device. Methods: A comprehensive list of validated drug-disease-food interactions from several reputable sources was constructed. This was compiled into a knowledge graph using the RACE array logic platform. This interactions knowledge graph was used to power a personalized dietary advisor application on a mobile device. Results: Data from over 500,000 drug-disease-food interactions including 1,699 food ingredients and 9,526 disease interactions were compiled into a highly compressed knowledge model. This was used to inform recommendations for individual complex patients. It was also tested on virtual population of 10,000 multimorbid and polypharmaceutical patients. Conclusions: This study showed that digital health tools can provide highly contextual and adaptive responses from a single knowledge graph. The study showed it is possible to provide highly personalized health advice to complex patients in real-time on their own mobile device without having to hold such private information on a server. This enables highly secure, private and personalized digital health tools to be built.


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