| ORIGINAL ARTICLE |
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| Year : 2022 | Volume
: 8
| Issue : 1 | Page : 20 |
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Diagnostic performance of reduced field-of-view diffusion-weighted imaging-targeted biopsy in suspected prostate cancer patients: A comparison with systematic biopsy
Tingyue Qi, Haiyan Cao, Hongguang Sun, Fang Du, Hao Feng, Xin Rong, Qibing Fan, Lei Wang
Department of Ultrasound, Medical Imaging Center, Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, China
Correspondence Address:
Tingyue Qi
Department of Ultrasound, Medical Imaging Center, Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou
China
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/digm.digm_3_22
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Purpose: To clarify the diagnostic performance of reduced field-of-view (rFOV) diffusion-weighted imaging (DWI) and compare prostate cancer (PCa) detection rates of rFOV DWI-targeted biopsy (rFOV DWI-TB) with systemic biopsy (SB). Materials and Methods: Ninety-eight consecutive patients with suspected PCa (mean prostate-specific antigen [PSA]: 17.85 ng/mL, range, 4–28 ng/mL) were prospectively enrolled in this study. All rFOV DWI data were carried out using PI-RADS V 2.0 assessment category. All patients underwent a 10-core SB and a further 2–4 cores of rFOV DWI-TB. The performance of rFOV DWI was analyzed, and the cancer detection rates between two methods were compared. Results: The sensitivity, specificity, positive predictive value, and negative predictive value for detecting PCa with rFOV DWI were 85.11%, 92.16%, 90.91%, and 87.04%, respectively. Area under curve for rFOV DWI was 0.886. In the digital rectal examination (DRE) normal and PSA ≥ 10 ng/mL subgroups, the PCa detection rates were statistically greater for rFOV DWI-TB than for SB (both P < 0.05). The mean Gleason score of cancers detected by rFOV DWI-TB was significantly higher than that detected by SB (P < 0.05). In addition, the detection rate for rFOV DWI-TB cores was significantly better than for SB cores (P < 0.001). Conclusion: RFOV DWI allowed for good diagnostic performance in patients suspected of PCa. It may be useful for clinically significant PCa detecting.
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